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AG1 vs IM8 vs Tmrw: Breaking Down the Real Differences
Something's changing in how people think about daily health, and it starts with asking better questions: Not "What can I take to feel better today?" but "What supports my body's ability to perform, repair, and adapt over the long term?
This shift explains why foundational supplements have moved beyond basic multivitamins and greens powders. The most forward-thinking formulas are now addressing the 12 hallmarks of aging - the cellular and systemic processes that determine how well your body functions today and how resilient it remains over time.
This is where all-in-one foundational formulations claim to shine. But despite similar marketing language, AG1, IM8, and Tmrw are not built the same. Their ingredient strategies, dosing principles, and scientific frameworks reflect completely different philosophies of what “foundational health” actually means.
If you’ve ever wondered which formula delivers the most complete, science-aligned daily support, this breakdown reveals where each one stands - and why the differences matter more than most people realize.
Foundational Nutrition: What Should It Actually Achieve?
Before comparing brands, it’s important to understand what a foundational supplement should provide. A true all-in-one daily formula isn’t meant to simply fill micronutrient gaps, it should support the underlying systems that influence how well you function day to day and how resilient your body remains over time.
A complete foundational formula supports:
- Daily micronutrient balance
- Gut health and digestive comfort
- Cellular energy output
- Longevity systems support (cellular renewal + resilience)
- Detoxification pathways
- Stress response and mental clarity
- Inflammation balance
- Long-term biological repair processes
AG1 and IM8 address parts of this list. Tmrw addresses all of it.
Different Products, Different Goals
We haven’t included products like Tru Niagen or lower-cost blends like Agemate in the full comparison below, and that’s intentional. They’re built for a different purpose: Tru Niagen is primarily a single-ingredient approach, and Agemate competes mainly on price as a basic longevity starter. Our comparison focuses on comprehensive, daily foundational formulas where the question isn’t “what’s the cheapest option?” but “what’s the strongest all-rounder for long-term use, health-span, and performance.” If you’re choosing purely based on one ingredient or a lower price point, those options exist, they’re just not competing in the same category. (If you’re considering Agemate specifically, we’ve broken it down in detail in a separate blog - read more here.)
AG1: Broad Coverage With Limited Specificity
AG1 is built on a legacy greens-based template: lots of plants, large blends, and a generalist wellness approach. It’s effective for broad nutritional insurance, but it lacks targeted depth.
Where AG1 succeeds:
- Strong greens profile
- Basic gut support with probiotics and enzymes
- Essential vitamins and minerals
- Easy daily routine
Where AG1 falls short:
- No NMN, CaAKG, Spermidine, Urolithin A, Fisetin, TMG
- Heavy reliance on proprietary blends
- Stevia aftertaste
- No NAD⁺ precursors or targeted longevity actives
- No vitamin D (sold separately as AG Vitamin D3+K2)
IM8: Cleaner and More Modern, But Still Not Longevity-Oriented
IM8 improves on AG1’s structure. It’s more curated, offers better micronutrient density, and includes adaptogens. But despite a long ingredient list, it still lacks most compounds needed for true cellular support.
Where IM8 succeeds:
- More thoughtful structure than AG1
- Adaptogens for stress resilience
- Improved micronutrient composition
Where IM8 falls short:
- Not truly all-in-one: you need 2 separate daily drinks (Essentials + Longevity) to get full coverage Tmrw provides with one drink.
- Missing CaAKG: 0 mg included.
- Gut support is narrower: only 2 probiotic strains shown vs 9 strains + 1 spore strain (Tmrw) at 10B CFU.
- Not all-in-one NMN support: IM8 has no NMN in Essentials. It’s only in the separate Longevity drink, so you need two products every day to get it.
Tmrw: Built Backwards From Cellular Science
Tmrw begins with the question: “Which cellular pathways most influence long-term resilience and biological performance?”. From there, the formula is engineered using compounds validated in human research, with doses clear and clinically aligned.
What Tmrw includes:
- 35+ longevity compounds
- 9 probiotic strains + 1 spore strain
- Activated B-vitamins
- Detox botanicals
- Mitochondrial cofactors and NAD+ boosters
- Adaptogen + nootropic support
- Full dosing transparency
- NSF-certified manufacturing
Instead of trying to be a greens drink with extras, Tmrw is built as a complete longevity foundation for modern biology, the first of its kind.
Gut Health & Digestive Support
All three brands include probiotics, but quality, diversity, and transparency differ drastically.
AG1
- Probiotics & enzymes included
- 5 strains, 10B CFU
- Narrower strain diversity
IM8
- Some probiotic support
- Low strain diversity
- CFU presented, but strain breadth is limited
- Leans on spore-based strains vs broad-spectrum diversity
Tmrw
- 9 clinically studied strains + 1 spore strain
- 10B CFU total
- Prebiotics + digestive enzymes
- Botanicals supporting gut lining & digestion
Beyond digestion, gut diversity plays a role in mood, inflammation balance, and metabolic signaling. This is why Tmrw prioritizes strain variety rather than just CFU volume. A diverse microbiome offers more robust, long-term support across the body’s interconnected systems.
Taste & Daily Experience
Taste determines compliance, and compliance determines results.
AG1: Noticeable stevia aftertaste
IM8: Slightly cleaner, and now stevia-free
Tmrw: Sweetened with thaumatin for a clean, subtle, long-term-friendly flavor
Thaumatin avoids the bitterness, metallic notes that is often described as tasting “medicinal”, and digestive sensitivity stevia often causes over time, an important consideration for a product meant to be used daily for years.
Clinical Dosing Reality Check
Many all-in-one formulas tout impressive ingredient lists, but "pixie dusting" - tiny, ineffective doses - undermines real results. Proprietary blends exacerbate this, lumping actives into low total mg groups to pad labels without therapeutic impact. Here's how AG1 and IM8 stack up against clinical evidence, with Tmrw's precision doses for contrast.
The Proprietary Blend Problem
AG1 packs 75+ ingredients into two large blends, its “Active Superfood and Prebiotic Complex” and “Daily Phytonutrient Complex,” without listing individual doses. IM8 uses 9 blends. Its “Cell Rejuvenation Technology 8” squeezes six actives, including spermidine and berberine, into just 100mg total. Low-mg groups like these pad ingredient lists but can’t deliver the doses used in human studies. Tmrw discloses the dose of every key longevity active.
Ingredient Considerations: How AG1, IM8 and Tmrw Differ
All-in-one formulas often contain similar categories of ingredients, but the levels and types chosen can carry different considerations depending on the individual.
Below is a breakdown of key differences:
Vitamin C
- AG1: 500mg
- IM8: 900mg
- Tmrw: 400mg
Very high supplemental vitamin C intake (typically ≥1000mg/day) has been associated in some studies with increased kidney stone risk in certain populations, particularly men.
AG1 and especially IM8 push high-antioxidant strategies near upper limits; Tmrw's balanced 400mg prioritizes safety within a complete formula.
Licorice Root (Blood Pressure Consideration)
- AG1: Includes licorice root
- Tmrw: Does not include licorice root
Licorice root containing glycyrrhizin has been associated with increases in blood pressure and reductions in potassium levels in some individuals, particularly at higher intakes or with prolonged use.
Tmrw does not include licorice root in its daily formula.
Berberine / Dihydroberberine
- IM8: Berberine HCl (undisclosed dose)
- Tmrw: Not included
Berberine has been shown in human studies to inhibit key drug-metabolising enzymes. These enzymes are involved in processing a wide range of medications, including certain statins, antidepressants, beta blockers, blood pressure medications, anticoagulants such as warfarin, and sedatives like midazolam.
Because of this, some consumers prefer to use berberine intentionally and separately rather than include it automatically in a daily “essentials” formula.
Tmrw does not include berberine-style actives in its core blend.
Probiotic Strategy
- AG1: Multi-strain blend
- IM8: 10B CFU including Bacillus coagulans + Bacillus subtilis (spore strains)
- Tmrw: 9 strains + 1 spore strain
Spore-based probiotics like Bacillus species are valued for their durability because they survive heat, moisture, and stomach acid extremely well. That stability is one reason they’re commonly included in modern formulas.
However, spore strains function differently from traditional lactobacillus and bifidobacterium strains. They are transient, soil-derived organisms and are not designed to colonise the gut in the same way as classic probiotic strains.
Tmrw combines 9 traditional lactobacillus and bifidobacterium strains with a single spore strain, aiming to provide:
- Broader strain diversity
- Everyday digestive compatibility
- Stability without building the formula primarily around spore organisms
- A microbiome-support strategy that balances resilience and familiarity
Rather than centring the probiotic system around one dominant philosophy, Tmrw integrates both approaches in a measured way.
B6: Why Tmrw Keeps the Dose Low
AG1 and IM8 both contain 5mg of vitamin B6 per serving. Tmrw contains 2.5mg, half as much, in the bioactive P-5-P (pyridoxal-5-phosphate) form.
B6 shows up in multivitamins, energy drinks, magnesium blends and fortified foods, so daily intake from all sources adds up fast. Long-term high B6 intake has been linked to peripheral neuropathy, a form of nerve damage.¹
The Australian Therapeutic Goods Administration (TGA) has stated that peripheral neuropathy can occur at doses less than 50mg, and has noted “no minimum dose, duration of use or specific patient risk factors” have been identified as a safe threshold.² The TGA now requires warning labels on any product delivering more than 10mg of B6 per day.³
All three formulas sit below that warning threshold on their own. But the TGA’s position is that risk can’t be excluded below 50mg, particularly when people take several B6-containing products at once. A lower dose leaves more room for everything else in your diet and supplement routine.
Tmrw also uses P-5-P, the active coenzyme form the body uses directly, with no conversion step. Research explicitly recommends “PLP-based supplements are preferred over pyridoxine supplements because of minimal neurotoxicity observed in neuronal cell viability tests.”⁴
AG1's Lead Problem: What You Should Know
When a product is taken daily, safety isn’t just about individual ingredients, it’s about long-term exposure over time. Trace amounts of heavy metals like lead, cadmium, and arsenic can be present in raw materials. While these may be low on a single serving basis, consistency of use makes testing standards and transparency critical.
Independent, third-party testing plays an important role in verifying what’s actually present in a product beyond what’s listed on the label. In April 2025, ConsumerLab, an independent testing organization, published this update on its testing of AG1 (the formula sold before AG1 Next Gen):
These findings matter because heavy metals can build up in the body with daily use, and AG1 is marketed as a product to take every day, for years.
Tmrw holds NSF Certified for Sport certification, one of the most rigorous independent quality standards in the supplement industry. Our full Certificate of Analysis and NSF certification reports are published directly on this page, so you can verify exactly what is and isn't in every scoop.
Where AG1 Is Made
AG1 was made entirely in New Zealand for years. Around 2022, production shifted largely offshore, and AG1 sold in the US is now made in Utah.
Tmrw is still made in New Zealand, and every batch is NSF Certified for Sport. When you take something every day, it’s worth knowing exactly where it comes from.
Price, Taste, Value, and Extras
Tmrw is the clear value winner because it delivers full-spectrum, one-scoop coverage at USD $89/month on subscription. AG1 is cheaper at USD $79/month, but it’s also the no-frills greens play, priced like a basic foundation (and travel packs typically cost more).
The real gap shows up with IM8: to get comparable breadth, you’re pushed into two products - Essentials ($89/mo) + Longevity ($119/mo) - which puts the “matched” routine at $208 a month.
Net: IM8 costs USD $119 more per month than Tmrw for split coverage, while Tmrw stays one routine, one scoop, one bill, the simplest setup that’s actually built for long-term compliance.
AG1 is the entry point, not the endpoint, and the price doesn’t reflect that. Without NMN, CaAKG, or a longevity layer, it’s a premium tag on a basic greens formula.
IM8’s “full stack” requires two products, pushing the real monthly cost to $208 - that’s over double Tmrw’s $89/month, despite the coverage being split across products and with several key actives still under-dosed or undisclosed in blends.
AG1 is the entry point, not the endpoint, and the price doesn’t reflect that. Without NMN, CaAKG, or a longevity layer, it’s a premium tag on a basic greens formula.
Taste
AG1: Started with its familiar sweet pineapple-vanilla base, and now comes in Original, Citrus and Berry. Even with more flavors, Reddit users report an artificial taste, especially around the newer Next Gen formula.
IM8: Smoother, more modern profile (acai/berry).
Tmrw: Designed for lifelong daily compliance, and sweetened with thaumatin (katemfe fruit) and real berries and pineapple from New Zealand farms for a clean finish. The flavor is naturally refreshing with subtly sweet blueberry + pineapple (berry/tropical notes), naturally colored with blue spirulina + butterfly pea, and stays smooth and easy to enjoy every day with cold water.
Welcome Kit: Everything You Need to Get Started
When you subscribe to Tmrw, you’re not just getting a month’s supply of nutrient-dense longevity blend. Your first order comes with a Welcome Kit designed to make your daily ritual seamless and enjoyable, at no extra charge.
- Tmrw Shaker, Scoop & Canister: Normally priced at $47, these essentials are included for free. The shaker makes mixing your drink effortless; the custom scoop ensures perfect portions; and the canister keeps your formula fresh and organized on your counter.
- Tmrw Travel Sachets (3 ct): Valued at $11 and also free, these single‑serving sachets tuck easily into your bag so you never miss a serving when you’re on the go. You can buy top-up travel sachets on the members store if you prefer the sachets.
Your subscription ships every four weeks, so there’s always a fresh pouch of Tmrw ready when you need it. With the Welcome Kit, you have everything you need to start your healthy aging routine and stay consistent, whether at home or traveling.
Final Verdict: Which One Wins?
AG1 delivers solid basic wellness, greens coverage and simple nutrition insurance. But it falls short on longevity actives (zero NMN or CaAKG), leaves out vitamin D, and has faced heavy metal concerns in independent testing.
IM8 feels more modern with refined nutrients and some longevity nods, but its NMN sits in a separate product, its probiotics rely on just two spore strains, its Essentials formula includes berberine at an undisclosed dose, and its B6 dose is double Tmrw’s. Plus, two drinks daily dilute compliance and simplicity, and get costly.
Tmrw operates in a different league entirely. This precision longevity system fuses foundational nutrition, 9 + 1 spore strain gut support, detox pathways, mitochondrial power, inflammation balance, and 35+ science-backed cellular actives, all in one clean scoop. No stevia aftertaste, no heavy metals (NSF-certified), and B6 kept to a gentle 2.5mg in its active P-5-P form. It's engineered not just for today's energy, but for how your body performs, repairs, and stays resilient over decades.
So, need basic greens? AG1 suffices. Want upgraded greens? IM8 might edge ahead. Crave future-proof health without the hidden dangers? Tmrw redefines what's possible.
Works Cited
- Hadtstein & Vrolijk, "Vitamin B6-Induced Neuropathy: Exploring the Mechanisms (2021), accessed January 30, 2026,
- TGA Safety Update, "Peripheral neuropathy with supplementary vitamin B6" (2022) , accessed January 30, 2026,
- TGA Media Release, "Stronger safety controls to be introduced for products containing vitamin B6" (2025) , accessed January 30, 2026,
-
Expert Consensus on Vitamin B6 Therapeutic Use (2025) , accessed January 30, 2026
- AG1 Lead Testing and Safety Concerns - ConsumerLab, accessed January 30, 2026,
- AG1 Ingredients Analysis - AG1 Product Detail, accessed January 30, 2026,
-
B6-Induced Peripheral Neuropathy Risks, accessed January 30, 2026
- CaAKG Biological Age Reduction Trial, accessed January 30, 2026,
- CoQ10 Q-SYMBIO Trial Heart Failure Results, accessed January 30, 2026,
- Fisetin Senolytic Benefits Study, accessed January 30, 2026,
- IM8 Daily Ultimate Essentials Formula - IM8, accessed January 30, 2026,
- IM8 Daily Ultimate Longevity Formula - IM8, accessed January 30, 2026,
- NMN Dosage RCTs for NAD+ Boost, accessed January 30, 2026,
- Spermidine Autophagy Benefits Review, accessed January 30, 2026,
- AG1 Next Gen Taste Complaints - Reddit, accessed January 30, 2026,
- AG1 Taste Feedback - Reddit, accessed January 30, 2026,
- Tmrw vs Agemate Evolution Blog, accessed January 30, 2026,
- Total, Dietary, and Supplemental Vitamin C Intake and Risk of Incident Kidney Stones, accessed January 30, 2026,
- A low dose of daily licorice intake affects renin, aldosterone, and home blood pressure in a randomized crossover trial, accessed January 30, 2026, https://www.sciencedirect.com/science/article/pii/S0002916524000194
- Repeated administration of berberine inhibits cytochromes P450 in humans, accessed January 30, 2026, https://pmc.ncbi.nlm.nih.gov/articles/PMC4898966/
- Bacillus Probiotics: Spore Germination in the Gastrointestinal Tract, accessed January 30, 2026, https://pmc.ncbi.nlm.nih.gov/articles/PMC127533
- AG1 Manufacturing Move from New Zealand - NZ Herald, December 10, 2024, https://www.nzherald.co.nz/business/ag1-supplement-under-scrutiny-for-liver-harm-reports/BO6FMESPXJBB3HDFJ7O5NGMZLA/
Disclaimer
†This comparison is for educational and informational purposes only and reflects publicly available product data as of October 8, 2026. Formulations, doses, and pricing for third-party brands are subject to change - we recommend verifying current details directly with each brand. Where a brand is marked as not included, this indicates the ingredient was not publicly disclosed or present in the formula at time of writing.
Nothing on this page constitutes medical advice. Tmrw is a product of Simply Tmrw Group. We have made every effort to ensure accuracy but accept no liability for changes to third-party products after the date of publication. Always consult a qualified healthcare professional before starting any new supplement, particularly if you are pregnant, nursing, or taking prescription medication.
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