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March 29, 2025

AG1 vs IM8 vs Tmrw: Breaking Down the Real Differences

Reviewed by Dr. Brian Ramos

PhD Neurobiology at Yale university

Written by Nicole P

Health content writer

Something's changing in how people think about daily health, and it starts with asking better questions: Not "What can I take to feel better today?" but "What supports my body's ability to perform, repair, and adapt over the long term?

This shift explains why foundational supplements have moved beyond basic multivitamins and greens powders. The most forward-thinking formulas are now addressing the 12 hallmarks of aging - the cellular and systemic processes that determine how well your body functions today and how resilient it remains over time.

This is where all-in-one foundational formulations claim to shine. But despite similar marketing language, AG1, IM8, and Tmrw are not built the same. Their ingredient strategies, dosing principles, and scientific frameworks reflect completely different philosophies of what “foundational health” actually means.

If you’ve ever wondered which formula delivers the most complete, science-aligned daily support, this breakdown reveals where each one stands - and why the differences matter more than most people realize.

 

Foundational Nutrition: What Should It Actually Achieve?

Before comparing brands, it’s important to understand what a foundational supplement should provide. A true all-in-one daily formula isn’t meant to simply fill micronutrient gaps, it should support the underlying systems that influence how well you function day to day and how resilient your body remains over time.


A complete foundational formula supports:


  • Daily micronutrient balance
  • Gut health and digestive comfort
  • Cellular energy output
  • Longevity systems support (cellular renewal + resilience)
  • Detoxification pathways
  • Stress response and mental clarity
  • Inflammation balance
  • Long-term biological repair processes


AG1 and IM8 address parts of this list. Tmrw addresses all of it.

Different Products, Different Goals

We haven’t included products like Tru Niagen or lower-cost blends like Agemate in the full comparison below, and that’s intentional. They’re built for a different purpose: Tru Niagen is primarily a single-ingredient approach, and Agemate competes mainly on price as a basic longevity starter. Our comparison focuses on comprehensive, daily foundational formulas where the question isn’t “what’s the cheapest option?” but “what’s the strongest all-rounder for long-term use, health-span, and performance.” If you’re choosing purely based on one ingredient or a lower price point, those options exist, they’re just not competing in the same category. (If you’re considering Agemate specifically, we’ve broken it down in detail in a separate blog - read more here.)

 

AG1: Broad Coverage With Limited Specificity

AG1 is built on a legacy greens-based template: lots of plants, large blends, and a generalist wellness approach. It’s effective for broad nutritional insurance, but it lacks targeted depth.

Where AG1 succeeds:

  • Strong greens profile
  • Basic gut support with probiotics and enzymes
  • Essential vitamins and minerals
  • Easy daily routine

Where AG1 falls short:

  • No NMN, CaAKG, Spermidine, Urolithin A, Fisetin, TMG
  • Heavy reliance on proprietary blends
  • Stevia aftertaste
  • No longevity or mitochondrial framework

 

 

IM8: Cleaner and More Modern, But Still Not Longevity-Oriented

IM8 improves on AG1’s structure. It’s more curated, offers better micronutrient density, and includes adaptogens. But despite a long ingredient list, it still lacks most compounds needed for true cellular support.

Where IM8 succeeds:

  • More thoughtful structure than AG1
  • Adaptogens for stress resilience
  • Improved micronutrient composition

Where IM8 falls short:

  • Not truly all-in-one: you need 2 separate daily drinks (Essentials + Longevity) to get full coverage Tmrw provides with one drink.
  • Missing CaAKG: 0 mg included.
  • Gut support is narrower: only 2 probiotic strains shown vs 10 strains (Tmrw) at 10B CFU.
  • Not all-in-one NMN support: IM8 has no NMN in Essentials, and its separate Longevity drink delivers 300 mg per serve vs 500 mg per serve in Tmrw.

 

 

Tmrw: Built Backwards From Cellular Science

Tmrw begins with the question: “Which cellular pathways most influence long-term resilience and biological performance?”. From there, the formula is engineered using compounds validated in human research, with doses clear and clinically aligned.

What Tmrw includes:

  • 35+ longevity compounds
  • 10 probiotic strains
  • Activated B-vitamins
  • Detox botanicals
  • Mitochondrial cofactors and NAD+ boosters
  • Adaptogen + nootropic support
  • Full dosing transparency
  • NSF-certified manufacturing

Instead of trying to be a greens drink with extras, Tmrw is built as a complete longevity foundation for modern biology, the first of its kind.

 

Gut Health & Digestive Support

All three brands include probiotics, but quality, diversity, and transparency differ drastically.

AG1

  • Probiotics & enzymes included
  • Dosing hidden in blends
  • Unclear strain diversity

IM8

  • Some probiotic support
  • Low strain diversity
  • CFU presented, but strain breadth is limited
  • Leans on spore-based strains vs broad-spectrum diversity

Tmrw

  • 10 clinically studied strains
  • 10B CFU total
  • Prebiotics + digestive enzymes
  • Botanicals supporting gut lining & digestion

Beyond digestion, gut diversity plays a role in mood, inflammation balance, and metabolic signaling. This is why Tmrw prioritizes strain variety rather than just CFU volume. A diverse microbiome offers more robust, long-term support across the body’s interconnected systems.

 

Taste & Daily Experience

Taste determines compliance, and compliance determines results.

AG1: Noticeable stevia aftertaste
IM8: Slightly cleaner, contains stevia in some formulas (in the Daily Ultimate Longevity formula)
Tmrw: Sweetened with thaumatin for a clean, subtle, long-term-friendly flavor


Thaumatin avoids the bitterness, metallic notes that is often described as tasting “medicinal”, and digestive sensitivity stevia often causes over time, an important consideration for a product meant to be used daily for years.

 

Clinical Dosing Reality Check

Many all-in-one formulas tout impressive ingredient lists, but "pixie dusting" - tiny, ineffective doses - undermines real results. Proprietary blends exacerbate this, lumping actives into low total mg groups to pad labels without therapeutic impact. Here's how AG1 and IM8 stack up against clinical evidence, with Tmrw's precision doses for contrast.

Ingredient Considerations: How AG1, IM8 and Tmrw Differ

All-in-one formulas often contain similar categories of ingredients, but the levels and types chosen can carry different considerations depending on the individual.
Below is a breakdown of key differences:

Vitamin C

  • AG1: 500mg
  • IM8: 900mg
  • Tmrw: 400mg

Very high supplemental vitamin C intake (typically ≥1000mg/day) has been associated in some studies with increased kidney stone risk in certain populations, particularly men.


AG1 and especially IM8 push high-antioxidant strategies near upper limits; Tmrw's balanced 400mg prioritizes safety within a complete formula.

Vitamin B12

  • AG1: 400mcg
  • IM8: 200mcg
  • Tmrw: 100mcg

High-dose vitamin B12 supplementation has been reported in the clinical literature to trigger acneiform eruptions in some individuals, particularly with higher dosing and extended use.

Tmrw keeps B12 at 100mcg, a measured daily level designed to support baseline function without pushing B12 as a headline dose.

Licorice Root (Blood Pressure Consideration)

  • AG1: Includes licorice root
  • Tmrw: Does not include licorice root

Licorice root containing glycyrrhizin has been associated with increases in blood pressure and reductions in potassium levels in some individuals, particularly at higher intakes or with prolonged use.

Tmrw does not include licorice root in its daily formula.

Berberine / Dihydroberberine

  • IM8: Berberine HCl (undisclosed dose)
  • Tmrw: Not included

Berberine has been shown in human studies to inhibit key drug-metabolising enzymes. These enzymes are involved in processing a wide range of medications, including certain statins, antidepressants, beta blockers, blood pressure medications, anticoagulants such as warfarin, and sedatives like midazolam. 



Because of this, some consumers prefer to use berberine intentionally and separately rather than include it automatically in a daily “essentials” formula.
Tmrw does not include berberine-style actives in its core blend.

Probiotic Strategy

  • AG1: Multi-strain blend
  • IM8: 10B CFU including Bacillus coagulans + Bacillus subtilis (spore strains)
  • Tmrw: 9 strains + 1 spore strain

Spore-based probiotics like Bacillus species are valued for their durability because they survive heat, moisture, and stomach acid extremely well. That stability is one reason they’re commonly included in modern formulas.

However, spore strains function differently from traditional lactobacillus and bifidobacterium strains. They are transient, soil-derived organisms and are not designed to colonise the gut in the same way as classic probiotic strains.

Tmrw combines 9 traditional lactobacillus and bifidobacterium strains with a single spore strain, aiming to provide:


  • Broader strain diversity
  • Everyday digestive compatibility
  • Stability without building the formula primarily around spore organisms
  • A microbiome-support strategy that balances resilience and familiarity

Rather than centring the probiotic system around one dominant philosophy, Tmrw integrates both approaches in a measured way.

 

AG1's Lead Problem: What You Should Know

According to ConsumerLab testing, AG1 was found to contain 2.1 micrograms (mcg) of lead per scoop. Based on this result, ConsumerLab advises that the product should be avoided by children and during pregnancy.

AG1’s own published specifications allow for up to 4.5 mcg of lead per scoop, calculated from their stated maximum of 0.38 mcg of lead per gram in a 12 g serving. That's lead, the same heavy metal in old paint, building up in kidneys and brain.
Daily for a year? You're eating 1,600mcg lead from "health." Tmrw: lab-tested clean.

Independent testing has raised further red flags. An external, independent analysis found that AG1 contained 9× higher lead levels than acceptable benchmarks, alongside detectable mercury and cadmium. 
This combination matters: heavy metals accumulate silently with daily use, and when paired with undisclosed flavour compounds, they introduce unnecessary toxic load into a product marketed for long-term, everyday health.

 

Price, Taste, Value, and Extras

Tmrw is the clear value winner because it delivers full-spectrum, one-scoop coverage at USD $89/month on subscription. AG1 is cheaper at USD $79/month, but it’s also the no-frills greens play, priced like a basic foundation (and travel packs typically cost more).

The real gap shows up with IM8: to get comparable breadth, you’re pushed into two products - Essentials ($89/mo) + Longevity ($119/mo) - which puts the “matched” routine at $196 (combined monthly bundle).

Net: IM8 costs USD $107 more per month than Tmrw for split coverage, while Tmrw stays one routine, one scoop, one bill, the simplest setup that’s actually built for long-term compliance.

IM8’s “full stack” requires two products, pushing the real monthly cost to ~$196 - that’s ~120% more than Tmrw’s $89/month, despite the coverage being split across products and with several key actives still under-dosed or undisclosed in blends.
AG1 is the entry point, not the endpoint, and the price doesn’t reflect that. Without NMN, CaAKG, or a longevity layer, it’s a premium tag on a basic greens formula.

 

Taste

AG1: Started with its familiar sweet pineapple-vanilla base and, as of mid-2025, expanded into Tropical, Citrus, and Berry variants. Even with more flavors, Reddit users report an artificial tasting, especially around the newer Next Gen formula.

IM8: Smoother, more modern profile (acai/berry). Essentials is stevia-free (uses Reb M), but Longevity includes stevia, which means if you’re taking the “full stack,” you’re back in stevia territory anyway.

Tmrw: Designed for lifelong daily compliance, and sweetened with thaumatin (katemfe fruit) and real berries and pineapple from New Zealand farms for a clean finish. The flavor is naturally refreshing with subtly sweet blueberry + pineapple (berry/tropical notes), naturally coloured with blue spirulina + butterfly pea, and stays smooth and easy to enjoy every day with cold water.

 

 

Welcome Kit: Everything You Need to Get Started

When you subscribe to Tmrw, you’re not just getting a month’s supply of nutrient-dense longevity blend. Your first order comes with a Welcome Kit designed to make your daily ritual seamless and enjoyable, at no extra charge.

  • Tmrw Shaker, Scoop & Cannister: Normally priced at $36, these essentials are included for free. The shaker makes mixing your drink effortless; the custom scoop ensures perfect portions; and the cannister keeps your formula fresh and organized on your counter.
  • Tmrw Travel Sachets (3 ct): Valued at $11 and also free, these single‑serving sachets tuck easily into your bag so you never miss a serving when you’re on the go. You can buy top-up travel sachets on the members store if you prefer the sachets.

Your subscription ships every four weeks, so there’s always a fresh pouch of Tmrw ready when you need it. With the Welcome Kit, you have everything you need to start your healthy aging routine and stay consistent, whether at home or traveling.

 

Final Verdict: Which One Wins?

AG1 delivers solid basic wellness - greens coverage and simple nutrition insurance. But it falls short on longevity actives (zero NMN or CaAKG), carries lead contamination risks (2.1-4.5mcg per scoop), and uses the neuropathy-prone B6 form.

IM8 feels more modern with refined nutrients and some longevity nods, but pixie-dusted doses (300mg NMN vs clinical 500mg+), spore-heavy probiotics that risk bloating, hidden berberine interactions, and 5mg synthetic B6 push it into risky territory. Plus, two drinks daily dilute compliance, simplicity and also become really costly.

Tmrw operates in a different league entirely. This precision longevity system fuses foundational nutrition, 10-strain gut support, detox pathways, mitochondrial power, inflammation balance, and 35+ clinically dosed cellular actives, all in one clean scoop. No stevia aftertaste, no heavy metals (NSF-certified), no nerve-damaging B6 (just safe 2.5mg P-5-P). It's engineered not just for today's energy, but for how your body performs, repairs, and stays resilient over decades.

So, need basic greens? AG1 suffices. Want upgraded greens? IM8 might edge ahead. Crave future-proof health without the hidden dangers? Tmrw redefines what's possible.

 

Welcome Kit: Everything You Need to Get Started

When you subscribe to Tmrw, you’re not just getting a month’s supply of nutrient-dense longevity blend. Your first order comes with a Welcome Kit designed to make your daily ritual seamless and enjoyable, at no extra charge.

  • Tmrw Shaker, Scoop & Cannister: Normally priced at $36, these essentials are included for free. The shaker makes mixing your drink effortless; the custom scoop ensures perfect portions; and the cannister keeps your formula fresh and organized on your counter.
  • Tmrw Travel Sachets (3 ct): Valued at $11 and also free, these single‑serving sachets tuck easily into your bag so you never miss a serving when you’re on the go. You can buy top-up travel sachets on the members store if you prefer the sachets.

Your subscription ships every four weeks, so there’s always a fresh pouch of Tmrw ready when you need it. With the Welcome Kit, you have everything you need to start your healthy aging routine and stay consistent, whether at home or traveling.

 

Works Cited

  1. AG1 Lead Testing and Safety Concerns - ConsumerLab, accessed January 30, 2026,
    https://www.consumerlab.com/answers/athletic-greens-ag1-is-it-worth-it/athletic-greens-ag1/
  2. AG1 Ingredients Analysis - AG1 Product Detail, accessed January 30, 2026,
    https://drinkag1.com/products/greens-powder-pouch
  3. B6-Induced Peripheral Neuropathy Risks, accessed January 30, 2026,
    https://pmc.ncbi.nlm.nih.gov/articles/PMC8483950/
  4. CaAKG Biological Age Reduction Trial, accessed January 30, 2026,
    https://clinicaltrials.gov/study/NCT07114536
  5. CoQ10 Q-SYMBIO Trial Heart Failure Results, accessed January 30, 2026,
    https://pmc.ncbi.nlm.nih.gov/articles/PMC10811087/
  6. Fisetin Senolytic Benefits Study, accessed January 30, 2026,
    https://www.nad.com/news/fisetin-fights-frailty-new-study-shows-supplment-preserves-strength
  7. IM8 Daily Ultimate Essentials Formula - IM8, accessed January 30, 2026,
    https://im8health.com/products/essentials
  8. IM8 Daily Ultimate Longevity Formula - IM8, accessed January 30, 2026,
    https://im8health.com/products/longevity
  9. NMN Dosage RCTs for NAD+ Boost, accessed January 30, 2026,
    https://www.frontiersin.org/journals/aging/articles/10.3389/fragi.2022.851698/full
  10. Spermidine Autophagy Benefits Review, accessed January 30, 2026,
    https://www.aging-us.com/article/101354/text
  11. AG1 Next Gen Taste Complaints - Reddit, accessed January 30, 2026,
    https://www.reddit.com/r/AthleticGreens/comments/1hnr0q3/notice_a_change_in_taste_as_of_late/
  12. AG1 Taste Feedback - Reddit, accessed January 30, 2026,
    https://www.reddit.com/r/KaraAndNate/comments/1f1n2zw/theres_no_way_ag1_taste_good/
  13. Tmrw vs Agemate Evolution Blog, accessed January 30, 2026,
    https://drinkTmrw.com/blogs/news/from-agemate-to-Tmrw-the-evolution-of-longevity-science
  14. Total, Dietary, and Supplemental Vitamin C Intake and Risk of Incident Kidney Stones, accessed January 30, 2026,
    https://pmc.ncbi.nlm.nih.gov/articles/PMC4769668/#:~:text=Two%20previous%20epidemiologic%20studies%20have,3%2C12%2C15
  15. Vitamin B12 modulates the transcriptome of the skin microbiota in acne pathogenesis
    https://pmc.ncbi.nlm.nih.gov/articles/PMC6049814/
  16. A low dose of daily licorice intake affects renin, aldosterone, and home blood pressure in a randomized crossover trial
    https://www.sciencedirect.com/science/article/pii/S0002916524000194
  17. Repeated administration of berberine inhibits cytochromes P450 in humans
    https://pmc.ncbi.nlm.nih.gov/articles/PMC4898966/

 

Disclaimer

†This comparison is for educational and informational purposes only. If a comparison brand does not have a tick, this indicates the ingredient is not included. Product details are based on publicly available sources as of October, 2025.

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